Innovative Solutions for Live Cell Analysis and Immunohistochemistry

Jens Bauer, Enzo Life Sciences
Thursday, June 8 2017, 11.15 - 12.45

Founded in 1976, Enzo was the first company to develop the non-radioactive labeling and detection of nucleic acids. Nowadays, Enzo offers a strong portfolio of antibodies, peptides, proteins, small molecules, labeling probe dyes and kits providing researchers with optimal tools for cellular analysis, gene expression analysis, high-content screening, nucleic acid detection, protein biochemistry and detection, and target identification/validation.

The use of fluorescent dyes to identify cell structural components and monitor cytotoxicity or cellular responses to growth signals is well established. In addition to a wide selection of gold standard labeling dyes such as DAPI, Hoechst, and JC-1, Enzo Life Sciences has translated its expertise in fluorescent probe chemistry and cellular analysis into our CELLESTIAL® portfolio of unique probe-based assays and reagents to meet the emerging needs of the life sciences and drug discovery markets. From simple organelle specific dyes for imaging cell structure and determining cell viability, to more complex dyes and reporter assays for monitoring cell signaling, death pathways, and toxicity, every product is developed and reliably manufactured to provide convenience, sensitivity, and specificity. A panel of the most innovative and popular dyes to look at autophagy, oxidative stress and protein aggregation (Fig. 1) will be described.

For decades, immunohistochemistry (IHC) has been an invaluable tool for the detection, localization, and quantification of antigens in preserved tissue for research and diagnostic purposes. Continuing our position as a leader in detection technologies, Enzo Life Sciences offers a complete set of tools to help improve the quality and efficiency of your IHC process from start to finish. Our high-sensitivity, low background POLYVIEW® PLUS reagents combined with the market’s most extensive palette of unique HIGHDEF® chromogens provide the accuracy and the flexibility needed for multiplex detection of two or more antigens on a single tissue section (Fig. 2) whilst eliminating false positive results and preserving precious tissue samples.


Figure 1

Figure 2